Body temperature is an essential indicator for the occurrence of infections and can be used as an indicator for the diseases outbreak already 72 hours before the actual fever (38.1 °C). In the project beforeFever, Fraunhofer ENAS explores manufacturing strategies for flexible and cost-effective wearables for temperature measurement on the human body to enable an initial indication or a follow-up of sick patients. By using and combining conventional printing technologies, flexible polymer films could be coated with graphical indicators and adapted thermochromic pigments with temperature indication from 37 °C. The future use of novel ultra-thin and breathable medical substrate materials is expected to extend the wearing time of the indicators up to 14 days. Therefore, this cost-effective measurement method is very well suited for use even in underserved regions or with very high patient numbers.